CKSauthorer: Semi-automated Authoring of Essential Clinical FAQs

Work in progress of Dr. Jonnalagadda's K99/R00 project at Mayo Clinic and Northwestern University:

The use of clinical knowledge systems such as UpToDate that provide reliable information at the point of care has been shown to improve patient safety and decision-making. However, because of the overabundance of clinical resources and guidelines, adding new content to UpToDate and ensuring that it is consistent with evidence is time consuming. This career grant proposes to investigate the feasibility of using a novel text mining based informatics approach to semi-automate the management of a clinical knowledge system, using UpToDate as the test bed. Although the methods will be applicable to any clinical knowledge system and any topic, they will be evaluated using two important test topics from cardiology – congestive heart failure and atrial fibrillation. While the existing content of UpToDate is private, the methods and the code we develop to assist in generating the content are being released incrementally.

This project was also funded partly by Mayo Clinic's internal resources.


Siddhartha Jonnalagadda
Majid Rastegar
Dingcheng Li
Soheil Moosavinasab
Hongfang Liu

Associated Institutions

Mayo Clinic
Northwestern University Biomedical Informatics Center (NUBIC)

Application Domains
  • Clinical
Other Resource Type
Software Subtype
  • Data mining / Machine learning
  • Document/information retrieval
  • NLP / information extraction
  • Text mining
Programming Languages
  • Java
Operating Systems
  • Linux
  • OS X
  • Unix
  • Windows
Included Components
  • Application Programming Interface
Dataset Subtype
Data Model Subtype
Online Resource Subtype
Knowledge Base Subtype
Intended User Types
  • NLP researcher or developer
  • Software developer
Available Documentation
  • API
Licensing Type
Open source
Development Milestones

Released the initial version on August 23, 2013. Expect more at the end of September to mark the transition of this project to Northwestern University from Mayo Clinic

Date of Latest Version